Record: 9-7
| EVENT | DATE | VENUE/CITY | |
| Pittsburgh Steelers vs. Tennessee Titans |
9/10/2009 | Heinz Field Pittsburgh, PA |
13-10 OT W |
| Chicago Bears vs. Pittsburgh Steelers |
9/20/2009 | Soldier Field Chicago, IL |
14-17 L |
| Cincinnati Bengals vs. Pittsburgh Steelers |
9/27/2009 | Paul Brown Stadium Cincinnati, OH |
20-23 L |
| Pittsburgh Steelers vs. San Diego Chargers |
10/4/2009 | Heinz Field Pittsburgh, PA |
38-28 W |
| Detroit Lions vs. Pittsburgh Steelers |
10/11/2009 | Ford Field Detroit, MI |
28-20 W |
| Pittsburgh Steelers vs. Cleveland Browns |
10/18/2009 | Heinz Field Pittsburgh, PA |
27-14 W |
| Pittsburgh Steelers vs. Minnesota Vikings |
10/25/2009 | Heinz Field Pittsburgh, PA |
27-17 W |
| Denver Broncos vs. Pittsburgh Steelers |
11/9/2009 | Invesco Field at Mile High Denver, CO |
28-10 W |
| Pittsburgh Steelers vs. Cincinnati Bengals |
11/15/2009 | Heinz Field Pittsburgh, PA |
12-18 L |
| Kansas City Chiefs vs. Pittsburgh Steelers |
11/22/2009 | Arrowhead Stadium Kansas City, MO |
24-27 OT L |
| Baltimore Ravens vs. Pittsburgh Steelers |
11/29/2009 | MT Bank Stadium Baltimore, MD |
17-20 OT L |
| Pittsburgh Steelers vs. Oakland Raiders |
12/6/2009 | Heinz Field Pittsburgh, PA |
24-27 L |
| Cleveland Browns vs. Pittsburgh Steelers |
12/10/2009 | Cleveland Browns Stadium Cleveland, OH |
6-13 L |
| Pittsburgh Steelers vs. Green Bay Packers |
12/20/2009 | Heinz Field Pittsburgh, PA |
37-36 W |
| Pittsburgh Steelers vs. Baltimore Ravens |
12/27/2009 | Heinz Field Pittsburgh, PA |
8-7 W |
| Miami Dolphins vs. Pittsburgh Steelers |
1/3/2009 | Dolphins Stadium Miami, FL |
30-24 W |
